How does this fit my own experience?
Though the only evident symptom of MS was great fatigue at the time, a French neurologist 30 years later stated that the disease began for me when I was 18. This implies that childhood stress in some way "deformed" my vascular system. (Remember, Dr. Zamboni and colleagues observed that MS patients had "deformed" veins in the back and neck.) Food intolerances, especially to wheat, could account for some of the stress. (There are 3 reasons for wheat intolerance; celiac disease, wheat allergies, or gluten insensitivity.) However, this is not specific to girls. Rather, from puberty age 12 I experienced terrible, monthly menstrual cramps. This alone could explain the higher incidence of female MS since the cramps occur monthly and seize up the entire body, including neck, back, and shoulders.
Between age 18 and the breakdown at age 32 all my major health problems were gynecological in origin. They caused stress, their treatment led to toxicity. The drugs "poisoned" my intestines, by age 32 I had the most rotten flatulence imaginable. From age 18 frequent bladder infections required antibiotic treatment. The female anatomy favors cystitus subsequent to intercourse, many women are subject to this problem. So right off we have trauma in the pelvic region as well as stress through toxicity. From age 18 I took birth control pills which in general sickened me. One brand caused nausea and weight gain. Another seemed to increase my blood pressure and one evening I thought my head would explode. I vowed that if I survived the night I would never take another birth control pill. And I didn't.
I developed endometriosis, a gynecological condition leading to intense pain and cramping. I was given DES stilboestrol, an endocrine disrupter, known to lead to breast cancer and liver failure. Then I was given Danazol, a modified testosterone, which can lead to ovarian cancer and liver problems.
When I detoxified and changed my diet at age 35, not only did the MS disappear, but the endometriosis disappeared as well. (So did the foul intestinal flatulence.) My gynecologist didn't want to believe this was possible. He is wrong. The origin of endometriosis is unknown (ditto MS), but think of the body absorbing foods (wheat) or medications (antibiotics) which it finds toxic. It fights to evict the poison but can't. It fights its own tissue where the toxins are imbedded, leading to all kinds of bizarre manifestations. (I won't describe the endometriosis, it's too disagreeable.)
So if more women than men develop MS it could well be because they have gynecological issues which both stress and poison the body.
An epidemiological questionnaire should ask 1) if the woman experienced menstrual cramps, starting when and with what severity 2) cystitus following intrcourse, treatment and frequency 3) birth control pills 4) endometriosis 5) any other gynecological disorder requiring hormone modifying treatment. Gynecologists could expand on this.
So I think I need to back-track on the personality factor in female MS and simply consider the gynecological problems which stress and require treatment leading to toxicity.